Summary of the experimental paradigm. n=12 mice/group were used in this experiment. On the first 2 habituation days (H1, H2), all mice received SAL. During the treatment phase, mice were treated daily with SAL or 1.8 g/kg i.p EtOH (D1-D15). On the day following the last ethanol injection (i.e., Day 16), mice underwent stereotaxic implantation of microdialysis guide cannula. On Day 20, microdialysis probes were implanted, and, microdialysis sample collection was performed on Day 21. A separate set of animals underwent identical ethanol or saline treatment but in lieu of microdialysis procedures, BECs were measured on Day 21. Star denotes assessment of open field locomotor activity.