. Author manuscript; available in PMC: 2013 Apr 21.

Published in final edited form as: Behav Brain Res. 2012 Feb 11;230(1):229–236. doi: 10.1016/j.bbr.2012.02.003

Table 3.

Baseline Acoustic Startle and Pre-Pulse Inhibition^a

Treatment	Sex	^bBaseline startle (N)	^c110 db Pre-Pulse Inhibition	^d120 db Pre-Pulse Inhibition
SA	M	0.214±0.030	76.367±4.073	48.690±6.124
THIO	M	0.253±0.039	71.893±4.792	52.889±4.425
MA	M	0.125±0.019	83.2460±9.940	57.748±8.646
SA	F	0.154±0.010	66.193±3.922	43.483±3.697
THIO	F	0.243±0.041	81.471±5.810	53.295±9.892
MA	F	0.216±0.035	59.959±8.124	33.415±9.456

Data are expressed as mean ± standard error of the mean.

Main effect of treatment on baseline startle (F(2,42)=3.456, p = 0.04) with THIO-treated mice having higher PPI.

Baseline-adjusted % PPI at 110 db. A significant sex × treatment interaction (F(2,42) = 3.81, p = 0.029 and a trend for a main effect of sex (p = 0.09) with males having higher PPI than females. Simple effects showed that male MA-treated mice had greater PPI than female MA-treated mice 110 db (p < 0.0068).

No effect of tx on 120 db baseline adjusted % PPI.

¹SA=saline; MA=methamphetamine; THIO=thioperamide. n = 8 mice/sex/treatment.