Table 1.
Enzyme Activitya,b |
|||||||
---|---|---|---|---|---|---|---|
Assay Type | Blank | Blank | Blank | Type A patient |
Type B patient |
Type C patient |
Type D patient |
MPS IIIA | 0.17 | 0.29 | 0.22 | 0.25 | 1.9 | 2.2 | 1.9 |
MPS IIIB | 0.00 | 0.11 | 0.01 | 2.8 | 0.11 | 2.0 | 2.3 |
MPS IIIC | 0.22 | 0.20 | 0.19 | 3.3 | 3.5 | 0.16 | 2.5 |
MPS IIID | 0.02 | 0.02 | 0.01 | 0.68 | 0.60 | 0.62 | 0.04 |
In units of nmol/(h mg protein).
From triplicate injections with coefficients of variation <10%.