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. Author manuscript; available in PMC: 2013 Apr 21.
Published in final edited form as: Behav Brain Res. 2012 Feb 2;230(1):34–39. doi: 10.1016/j.bbr.2012.01.042

Figure 3. Nicotine-associated cue-induced reinstatement of nicotine-seeking behavior.

Figure 3

Following the acquisition and extinction of nicotine- (A) or saline (B)-seeking behavior, this behavior was reinstated by the presentation of nicotine- or saline-associated light cues from the active nose-poke hole. One non-contingent cue presentation was given at the start of the session and subsequent cue presentations were given contingently for nose-pokes on an FR2 schedule (CUE condition). This reinstatement session was compared to the average of the two extinction sessions preceding testing (BSL condition). Data is shown as mean (±SEM) number of nose-pokes in the active hole. **p<0.01, Student’s t-test.