Table 4.

Predictors of Current or Past Warfarin Use in Hemodialysis Patients with Atrial Fibrillation

	Crude		Fully-adjusted
	Odds Ratio	95% CI	Odds Ratio	95% CI
Age 75 to <85 years (vs. 66 to <75 years)	0.99	0.81 – 1.21	0.93	0.75 – 1.15
Age ≥ 85 years (vs. 66 to <75 years)	0.79	0.60 – 1.05	0.71	0.53 – 0.95
Female (vs. Male)	1.06	0.87 – 1.29	1.04	0.85 – 1.29
Non-White Race (vs. Caucasian)	0.57	0.45 – 0.72	0.59	0.46 – 0.76
Medicaid (vs. no Medicaid beneficiary)	0.78	0.63 – 0.95	0.86	0.69 – 1.07
1-3 years (vs. <1 year since since first ESRD treatment)	0.98	0.84 – 1.15	0.96	0.81 – 1.14
>3 years (vs. <1 year since since first ESRD treatment)	0.84	0.68 – 1.02	0.83	0.66 – 1.05
Comorbidities (vs. absence of comorbidity)
Diabetes	0.90	0.72 – 1.12	0.91	0.72 – 1.14
Hypertension	0.94	0.42 – 2.08	0.96	0.45 – 2.05
Heart failure	1.20	0.80 – 1.79	1.18	0.77 – 1.81
Coronary artery disease	1.09	0.87 – 1.36	1.02	0.81 – 1.28
Peripheral artery disease	1.14	0.93 – 1.40	1.12	0.91 – 1.39
Chronic obstructive pulmonary disease	1.13	0.94 – 1.36	1.09	0.90 – 1.33
Cancer (excl. non-melanoma skin cancer)	1.04	0.80 – 1.34	1.06	0.81 – 1.39
Cerebral Ischemia	1.04	0.87 – 1.24	1.07	0.88 – 1.30
Intracranial bleed	1.05	0.66 – 1.67	1.05	0.64 – 1.73
Gastrointestinal bleed	0.84	0.70 – 1.01	0.87	0.71 – 1.06
Peptic ulcer disease	0.81	0.62 – 1.05	0.88	0.66 – 1.18
Liver disease	0.63	0.42 – 0.93	0.67	0.45 – 1.00
Dementia	0.72	0.56 – 0.91	0.81	0.62 – 1.06
Depression	1.01	0.81 – 1.25	0.98	0.78 – 1.23
History of falls or fractures	0.90	0.72 – 1.12	0.84	0.66 – 1.06
Prior nursing home stay	0.88	0.73 – 1.05	0.82	0.67 – 1.01
Deep venous thrombosis	2.10	1.70 – 2.59	2.26	1.81 – 2.84
Pulmonary embolism	1.43	1.14 – 1.78	1.31	1.03 – 1.67
Valvular disease or repair	1.17	0.97 – 1.40	1.10	0.91 – 1.35
History of vascular thrombosis	0.95	0.76 – 1.18	0.86	0.67 – 1.09

Multivariable model also adjusted for calendar year. Crude and adjusted associations of calendar year with current or past warfarin use are shown in Figure 3. Abbreviation: ESRD – end-stage renal disease.