Table 1.
Demographic variable | Frequency (n=149) | Percentage (%) |
---|---|---|
Sex | ||
Male | 84 | 56 |
Female | 65 | 44 |
Race | ||
Other | 29 | 20 |
Black | 28 | 19 |
White | 92 | 62 |
Diagnosis | ||
Nonmalignant | 33 | 22 |
Malignant | 116 | 78 |
Primary diagnosis | ||
Others | 87 | 58 |
Lymphoid malignancies & aplastic anemia | 62 | 43 |
Survival status | ||
Dead | 28 | 19 |
Alive | 121 | 81 |
BMI at alloHCT* | ||
Normal & underweight | 96 | 67 |
Overweight & obese | 47 | 33 |
Age at MR** | ||
<10 | 51 | 34 |
≥10 | 98 | 66 |
Age at alloHCT | ||
<10 | 65 | 44 |
≥10 | 84 | 56 |
Conditioning regimen | ||
Total body irradiation | 101 | 68 |
No-total body irradiation | 48 | 32 |
Physis status at allo HCT | ||
Closed | 42 | 28 |
Open | 107 | 72 |
Acute GVHD maximum Overall grade | ||
No acute GVHD | 30 | 20 |
Grade 1, 2 | 81 | 54 |
Grade 3, 4 | 38 | 26 |
Chronic GVHD grade | ||
No chronic GVHD | 92 | 62 |
Limited | 26 | 18 |
Extensive | 31 | 21 |
Donor type | ||
Unrelated | 57 | 381 |
Related | 92 | 62 |
Donor match type | ||
HLA-matched siblings | 49 | 33 |
Matched unrelated donors | 57 | 38 |
Mismatched family members | 43 | 29 |
Product type | ||
HPC-A | 47 | 32 |
HPC-C | 1 | 1 |
HPC-M | 101 | 68 |
Duration of chronic GVHD | ||
No prior chronic GVHD | 92 | 62 |
Duration ≤ 6 months | 39 | 26. |
Duration > 6 months | 18 | 12 |
BMI calculated only for children more than 2 years old.
Age at the first peak osteonecrosis, if a patient did not have any positive imaging result; age at the last imaging date was used.
Abbreviations: alloHCT, allogeneic hematopoietic stem cell transplantation; BMI, Body mass index; GVHD, Graft vs. host disease;; HPC-A, Hematopoietic stem cell from peripheral blood; HPC-M, Hematopoietic stem cell from Marrow; HPC-C, Hematopoietic stem cell from cord; MR, magnetic resonance imaging