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. 2012 Feb 22;32(8):2683–2695. doi: 10.1523/JNEUROSCI.4125-11.2011

Figure 12.

Figure 12.

Kainate-induced cell death in the hippocampus is reduced by the RGS4 inhibitor CCG-4986 (CCG). Hippocampal slices of WT mice were collected 7 d after indicated treatment and stained by hematoxylin and eosin (HE, A, B). Cell death was detected by Fluoro-Jade B (FJB) staining (C, D) and TUNEL assay (E, F). Significant neuronal cell death was detected in hippocampus from mice treated with kainate, but not in hippocampus from mice cotreated with kainate (KA) and CCG-4986.