Table 3.

Values of glass transition temperature for raw polymer, empty NSs, and FB-loaded NSs before and after γ-irradiation

	Tg (°C)
	Nonirradiated	γ-irradiated
PLGA 75:25 raw polymer	59.44	52.84*
PLGA 75:25 NS	57.62	53.51*
PLGA 75:25 + FB NS	47.25	47.44
PLGA 50:50 raw polymer	54.18	49.78*
PLGA 50:50 NS	49.05	46.43*
PLGA 50:50 + FB NS	44.48	45.87
PLGA 50:50–PEG 5% raw polymer	49.09	34.58*
PLGA 50:50–PEG 5% NS	48.45	43.76*
PLGA 50:50–PEG 5% + FB NS	41.41	42.54
PLGA 50:50–PEG 10% raw polymer	46.09	35.99*
PLGA 50:50–PEG 10% NS	43.33	37.95*
PLGA 50:50–PEG 10% + FB NS	42.45	40.51
PLGA 50:50–PEG 15% raw polymer	43.82	33.85*
PLGA 50:50–PEG 15% NS	42.53	38.56*
PLGA 50:50–PEG 15% + FB NS	39.55	38.78

Note:

^*P < 0.05 against nonirradiated samples.

Abbreviations: FB, flurbiprofen; NSs, nanospheres; PLGA, Poly(D,L-lactide-co-glycolide); PLGA–PEG, poly(D,L-lactide-co-glycolide) with poly(ethylene glycol); T_g, glass transition temperature.