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(A) Brain/blood radioactivity ratio and (B) brain distribution of radioactivity following one or two intravenous or intranasal doses of dendriplexes in rats.
Note: *P < 0.05 (statistically significant difference).
Abbreviations: IV, intravenous; DX, dendriplex; LX, lipoplex; siRNA, short interference RNA; PxCBP, poloxamer/carbopol gel.
