Table 3.
Age | Mean | MoE for LOAEL of 8,000 ng/kg/day | MoE for TD05of 19,600 ng/kg/day | p90 | MoE for LOAEL of 8,000 ng/kg/day | MoE for TD05 of 19,600 ng/kg/day |
---|---|---|---|---|---|---|
0-2 months | 2.22 | 3,604 | 8,829 | 6.07 | 1,318 | 3,229 |
3-5 months | 1.93 | 4,145 | 10,155 | 5.18 | 1,544 | 3,784 |
6-8 months | 2.45 | 3,265 | 8,000 | 5.88 | 1,361 | 3,333 |
9-11 months | 3.45 | 2,319 | 5,681 | 7.43 | 1,077 | 2,638 |
1 year | 4.38 | 1,826 | 4,475 | 8.66 | 924 | 2,263 |
2 years | 4.36 | 1,835 | 4,495 | 7.88 | 1,015 | 2,487 |
3 years | 4.22 | 1,896 | 4,645 | 7.81 | 1,024 | 2,510 |
4 years | 3.96 | 2,020 | 4,949 | 7.16 | 1,117 | 2,737 |
5-6 years | 3.66 | 2,186 | 5,355 | 6.77 | 1,182 | 2,895 |
7-11 years | 2.6 | 3,077 | 7,538 | 4.72 | 1,695 | 4,153 |
12-18 years | 1.76 | 4,545 | 11,136 | 3.25 | 2,462 | 6,031 |
19-30 years M | 1.76 | 4,545 | 11,136 | 3.4 | 2,353 | 5,765 |
31-50 years M | 1.62 | 4,938 | 12,099 | 3.06 | 2,614 | 6,405 |
51-70 years M | 1.43 | 5,594 | 13,706 | 2.73 | 2,930 | 7,179 |
71+years M | 1.33 | 6,015 | 14,737 | 2.58 | 3,101 | 7,597 |
12-18 years F | 1.41 | 5,674 | 13,901 | 2.53 | 3,162 | 7,747 |
19-30 years F | 1.33 | 6,015 | 14,737 | 2.54 | 3,150 | 7,717 |
31-50 years F | 1.33 | 6,015 | 14,737 | 2.54 | 3,150 | 7,717 |
51-70 years F | 1.23 | 6,504 | 15,935 | 2.35 | 3,404 | 8,340 |
71+years F | 1.15 | 6,957 | 17,043 | 2.23 | 3,587 | 8,789 |
LOAEL = lowest observed adverse effect level; TD05 = tumorigenicdose associated with a 5% increase in tumor incidence above background.