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. 2011 Oct;17(10):1839–1845. doi: 10.3201/eid1710.101825

Table 2. Bacteria isolated by culture of blood and pleural fluid samples and by PCR of pleural fluid samples from children with empyema, Australia, 2007–2009*.

Organism No. (%) positive samples
Blood culture,
n = 152 Pleural fluid
Culture,
n = 160 PCR,
n = 145
Streptococcus pneumoniae 19 (12.5) 12 (7.5) 74 (51)
S. pyogenes 3 (2.0) 14 (8.8) NA
S. milleri NA 4 (2.5) NA
MSSA 1 (0.7) 11 (6.8) 6 (4.1)
MRSA 1 (0.7) 6 (3.8) 7 (4.8)
Coagulase-negative staphylococci 4 (2.6) 2 (1.3) NA
Haemophilus influenzae 1 (0.7) NA 4 (2.8)
Mycobacterium tuberculosis NA 1 (0.6 NA
Pseudomonas aeruginosa NA 1 (0.6) NA
Mycoplasma pneumoniae NA NA 1 (0.7)
Chlamydia pneumoniae NA NA 1 (0.7)
Other† 4 (2.6) 4 (2.5) NA

*NA, not applicable; MSSA, methicillin-susceptible Staphylococcus aureus; MRSA, methicillin-resistant S.s aureus.
†Blood cultures: 1 isolate each of Streptococcus sanguinis; Staphylococcus hominis (from a specimen in which S. aureus was also isolated); Neisseria meningitidis; and Actinomyces naeslundii. Pleural fluid: 1 isolate each of Streptococcus oralis; Staphylococcus cohni; Eikenella corrodens; and Bacteroides fragilis (the last 2 from the same specimen, from which S. milleri was also isolated). Both MRSA and MSSA were cultured from 1 pleural fluid specimen.