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. 2012 Apr;341(1):43–50. doi: 10.1124/jpet.111.186833

Fig. 5.

Fig. 5.

Salsolinol-induced depression of sIPSC frequency is prevented by naltrexone (NAL) or DAMGO. A1, current traces obtained at the times indicated in A2. A2, incidence of sIPSCs during application of salsolinol (0.1 μM) in the presence of naltrexone. A3 and A4, pooled data (means ± S.E.M.; n = 6) show the lack of effect of salsolinol in the presence of naltrexone (5 μM) (frequency, A3; amplitude, A4). Numbers of cells are indicated in parentheses. B1, current traces obtained at the times indicated in A2. B2, time course of depression of sIPSC frequency by DAMGO (1 μM), which cancels the effect of salsolinol. B3 and B4, pooled data (means ± S.E.M.; n = 5) summarize these results (frequency, B3; amplitude, B4). *, p < 0.05, paired t test for DAMGO (b) or DAMGO + SAL versus pretreatment condition.