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. 2012 Apr;341(1):33–42. doi: 10.1124/jpet.111.187963

Fig. 4.

Fig. 4.

EtOH enhanced mIPSC and sIPSC frequency in a-VTA DA neurons. A1 and A2, representative histogram (A1) and traces (A2) show EtOH-induced increase in sIPSC frequency. A3, cumulative probability plots show little effect of EtOH on sIPSC amplitude. Inset is the mean ± S.E.M. of data from 15 cells. B1 and B2, representative histogram (B1) and traces (B2) showing EtOH-induced increase in mIPSC frequency. B3, cumulative probability plots indicate a robust increase in mIPSC amplitude. Inset is the mean ± S.E.M. of data from 15 cells. C, concentration dependence of EtOH facilitation (percentage increase) of frequency of sIPSCs and mIPSCs. For all concentrations, n = 8–12 neurons. EC50 was 30 ± 3 mM for sIPSCs and 41 ± 4 mM for mIPSCs.