Table 1. A comparison of FoldX energies with experimental values.

	Correlation coefficient
INDEX++	1	2	3	4	5	6	7	8	9
SPOT *	0.13	0.24	0.14	−0.09	0.25	0.14	0.07	0.34	0.16
MS Model +	0.57	0.31	0.50	0.60	0.16	0.53	0.47	0.52	0.62

The Pearson's correlation coefficients between the FoldX energies and the experimental data are shown.

⁺⁺ INDEX denotes a starting position in the 14-residue peptides to select representative fragment sequences for energy evaluation.

^* SPOT denotes pseudo-binding energies.

⁺ MS Model denotes the binding free energies derived from the MS model (MS-model energies).

We used 2010 SPOT synthesis data for amphiphysin from reference [12]. We took six consecutive residues in peptide sequences to evaluate the FoldX and MS-model energies.