Figure 6. Quantification of new and mature blood vessels.

A. The number of CD31 and aSMA positive blood vessels, or vessel density (number vessels per 100 µm²) was quantified in: intraperitoneally and subcutaneously induced endometriosis; eutopic endometrium (inside the uterus); muscular tissue of the abdominal wall either adjacent (peri-endometriotic) or distant to the induced lesions (muscle). The average number of vessels in each tissue for six mice is shown; statistic is based on unpaired Wilcoxon test: * = 0.002; ** = 0.029; ns = non-significantly different. B. The ratio between CD31 and aSMA positive blood vessels was calculated in corresponding locations (endometriosis, uterus, peri-endometriosis and muscle) in each mouse. Afterwards, the average CD31/aSMA ratio in each tissue was computed among the six mice. Statistic based on unpaired Wilcoxon test: * = 0.010; ** = 0.004; # = 0.030; ## = 0.019.