Table 1. Comparison of the predicted and the experimental amino acid preferences at each of the CDR interface positions.
28-L | 29-L | 30-L | 31-L | 32-L | |||||
Wji | pWji-ti | Wji | pWji-ti | Wji | pWji-ti | Wji | pWji-ti | Wji | pWji-ti |
P3.9 | S .61 | P4.2 | D .42 | G3.4 | S .65 | G4.3 | R .85 | R4.2 | F .43 |
A2.8 | N .56 | G2.4 | A .28 | F2.1 | A .57 | P3.7 | S .68 | A2.4 | Y .42 |
S1.4 | P .47 | M2.1 | N .18 | S1.7 | N .36 | N1.0 | A .57 | Y1.1 | H .37 |
E1.0 | F .40 | H1.0 | T .13 | A1.5 | H .31 | T0.2 | H .49 | W1.0 | N .36 |
M1.0 | A .19 | I1.0 | R .10 | P1.5 | P .23 | G .30 | G0.9 | G .25 | |
T0.9 | H .17 | T0.9 | L .08 | L .18 | N .20 | T0.2 | T .14 | ||
V0.2 | E .07 | L0.5 | H .07 | Y .07 | Y .07 | R .06 | |||
M .00 | A0.2 | I .05 | G .02 | A .00 | |||||
P .04 | R .01 |
At each position, the left-hand column shows the amino acid type and the corresponding Wji. All the predicted positive amino acid types (δpWji = 1) and the activation values for sequence preference (pWji) are shown in the right-hand column. The amino acid types shown in bold are the common amino acid types (true positives) shown in both the left-hand and the right-hand columns.