. Author manuscript; available in PMC: 2013 Oct 1.

Published in final edited form as: J Crit Care. 2011 Dec 15;27(5):526.e7–526.e12. doi: 10.1016/j.jcrc.2011.10.008

Table 2.

Global and regional cerebrovascular and metabolic response to osmotic agent

	Pre	Post
Global (minus focal injury)

CBF^*	30.9 ± 3.7	33.1 ± 4.2
CBV⁺	3.00 ± 0.35	3.15 ± 0.33
OEF	0.33 ± 0.07	0.33 ± 0.10
CMRO₂^*	1.42 ± 0.34	1.48 ± 0.41

Focal injury (CT hypo/hyper-intensity)

CBF^*	25.7 ± 9.1	27.3 ± 6.3
CBV⁺	2.74 ± 0.39	2.74 ± 0.55
OEF	0.38 ± 0.11	0.37 ± 0.08
CMRO₂^*	1.29 ± 0.27	1.36 ± 0.17

Baseline regions with CBF <25 (n=104)

CBF^*	18.6 ± 5.0	22.4 ± 6.4^a
CBV⁺	2.42 ± 1.46	2.56 ± 1.79^b
OEF	0.48 ± 0.24	0.41 ± 0.22^b
CMRO₂^*	1.34 ± 0.70	1.38 ± 0.56

CBF=cerebral blood flow, CBV=cerebral blood volume, OEF=oxygen extraction fraction, CMRO₂=cerebral metabolic rate for oxygen,

mL/100g/min,

⁺

ml/100g,

p< 0.001;

p< 0.05