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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Neurobiol Aging. 2011 Dec 14;33(6):1124.e1–1124.e12. doi: 10.1016/j.neurobiolaging.2011.11.011

Table 1.

Parameters of baclofen-stimulated GTP-binding in the hippocampus of young and aged F344 rats

Parameter Young Aged-Total Aged-Unimpaired Aged-Impaired
EMAX (% of young) 100.00 ± 10.33 99.30 ± 11.35 89.48 ± 12.88 107.50 ± 16.42
Log EC50 (M) −4.78 ± 0.18 −5.01 ± 0.24 −4.89 ± 0.26 −5.14 ± 0.36
Hill Slope (NH) 1.00 ± 0.34 0.69 ± 0.21 0.96 ± 0.47 0.59 ± 0.23