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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Arthritis Rheum. 2011 Apr;63(4):1054–1064. doi: 10.1002/art.30231

Figure 2.

Figure 2

Type I IFNR deletion abrogates IgG class-switch in 4-mo-old BXD2 mice. Representative spleen sections of BXD2, BXD2-Ifnar−/−, and B6 mice were stained with anti-IgM and anti-IgG antibodies as described in Materials and Methods. A, 20× objective lens magnification of images of spleen sections showing the presence of follicles and IgMbright or IgGbright B cells. B, 40× objective lens magnification of images of spleen sections, denoted with respect to the presence of a follicle (FO) whose boundary is denoted by broken lines.