Table 8.
Results of 5-HT1A mRNA and SERT levels in the hippocampus and hypothalamus of foetuses
Groups | n | Position | 5-HT1A mRNA(× 10-2) | SERT |
---|---|---|---|---|
Female foetuses of control | 47 | Hippocampus | 0.284 ± 0.051 | 0.312 ± 0.069 |
(0.269~0.299) | (0.292~0.332) | |||
Hypothalamus | 0.272 ± 0.031 | 0.342 ± 0.059 | ||
(0.263~0.281) | (0.325~0.359) | |||
Female foetuses of CUS | 43 | Hippocampus | 0.223 ± 0.036** | 0.213 ± 0.06** |
(0.212~0.234) | (0.194~0.232) | |||
Hypothalamus | 0.266 ± 0.059 | 0.246 ± 0.037** | ||
(0.248~0.284) | (0.234~0.258) | |||
Male foetuses of control | 40 | Hippocampus | 0.288 ± 0.051 | 0.334 ± 0.042 |
(0.272~0.304) | (0.320~0.348) | |||
Hypothalamus | 0.265 ± 0.044 | 0.351 ± 0.046 | ||
(0.251~0.279) | (0.336~0.366) | |||
Male foetuses of CUS | 49 | Hippocampus | 0.233 ± 0.042** | 0.226 ± 0.034** |
(0.221~0.245) | (0.216~0.236) | |||
Hypothalamus | 0.275 ± 0.028 | 0.235 ± 0.055** | ||
(0.267~0.283) | (0.219~0.251) |
Data are mean ± S.D. Data in bracket are 95% confidence intervals for each relevant statistic. 5-HT1A mRNA levels are the relative level of 5-HT1A to GAPDH. SERT levels are the relative level of SERT to β-actin. **: P < 0.01 compared with control by the same sex and the same position