Table 1. Results of testing for transmission of human and swine HEV to laboratory rats, Los Angeles, California, USA*.
| Inoculum |
Genotype |
ID50 |
No. injected |
No. with HEV RNA or antibodies against HEV |
| Sar 55 | 1 | 103.8† | 2 | 0 |
| Akluj-90 | 1 | 104.8† | 2 | 0 |
| Kashi-87 | 1 | 108.1‡ | 2 | 0 |
| Mex14 | 2 | 104.3† | 4 | 0 |
| Meng | 3 | 104.3§ | 4 | 0 |
| Meng | 3 | 102.3¶ | 4 | 0 |
*HEV, hepatitis E virus. The 50% infectious dose (ID50) was administered intravenously. †In human feces and titered in macaques. ‡Quantitative reverse transcription PCR titer. §In pig feces and titered in pigs. ¶In macaque feces and titered in macaques.