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. 2011 Dec;17(12):2294–2302. doi: 10.3201/eid1712.111002

Table 3. Associations between MBL2 haplotypes and invasive bacterial co-infection in fatal influenza in children and young adults, United States, 1998–99 through 2007–08 influenza seasons*.

Outcome Estimated odds ratio (95% CI)
Low producing
MBL2 haplotype† Intermediate or high producing
MBL2 haplotype‡ p value
MRSA, n = 8 7.1 (1.6–32.1) Referent 0.02
Staphylococcus aureus, n = 13 3.0 (0.8–11.2) Referent 0.11
Bacterial co-infection, n = 22 2.7 (0.9–8.6) Referent 0.10

*MBL2, mannose-binding lectin gene; MRSA, methicillin-resistant Staphylococcus aureus.
†includes MBL2 haplotypes O/O and XA/O.
‡includes MBL2 intermediate producer haplotypes XA/XA and YA/O and high producer haplotypes XA/YA and YA/YA.