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. 2012 Jan 6;119(9):1981–1987. doi: 10.1182/blood-2011-08-358135

Table 4.

Univariate and multivariate analyses for AP-CML and BP-CML

AP
BP
Univariate Multivariate Univariate Multivariate
HR P HR P HR P HR P
Age, y 1.02 .002 1.02 .02 1.01 .22 1.01 .04
Male sex 1.10 .65 1.97 .004 0.89 .39 0.79 .18
Splenomegaly 1.86 .01 1.51 .17 1.04 .82 1.004 .98
Hemoglobin, g/dL 1.04 .38 1.09 .26 1.03 .31 1.06 .12
White blood cell counts × 109/L 1.01 .35 0.999 .32 0.999 .96 1.000 .94
Platelet count × 109/L 1.002 .51 1.000 .55 0.999 .005 0.999 .006
Peripheral blasts, % 1.03 .009 0.98 .16 1.01 < .001 1.005 .15
Peripheral basophils, % 0.98 .10 0.98 .17 0.99 .19 0.99 .20
BM blasts, % 1.05 < .001 1.07 < .001 1.003 .16 0.997 .46
BM basophils, % 0.99 .56 1.06 .04 0.99 .36 1.02 .2
Y of therapy 0.947 < .001 0.93 < .001 0.97 < .001 0.956 < .001