Table 5.
Relationship between DIPSS covariate and HCT outcomes
| HCT outcome* | HR | 95% CI | P |
|---|---|---|---|
| Overall mortality | |||
| Age | 1.67 | 0.67-4.16 | .27 |
| Hemoglobin | 2.78 | 1.55-4.99 | < .001 |
| Leukocyte count | 0.94 | 0.53-1.63 | .81 |
| Peripheral blasts | 1.78 | 1.09-2.90 | .02 |
| Constitutional symptoms | 1.43 | 0.88-2.32 | .15 |
| Relapse or death | |||
| Age | 1.51 | 0.61-3.75 | .37 |
| Hemoglobin | 2.51 | 1.44-4.36 | .001 |
| Leukocyte count | 0.94 | 0.55-1.61 | .81 |
| Peripheral blasts | 1.71 | 1.07-2.73 | .02 |
| Constitutional symptoms | 1.43 | 0.89-2.30 | .14 |
| Relapse | |||
| Age | 0 | 0 | .99 |
| Hemoglobin | 1.13 | 0.45-2.88 | .80 |
| Leukocyte count | 1.84 | 0.73-4.69 | .20 |
| Peripheral blasts | 2.42 | 0.91-6.40 | .07 |
| Constitutional symptoms | 1.08 | 0.42-2.78 | .88 |
| NRM | |||
| Age | 1.99 | 0.79-5.00 | .14 |
| Hemoglobin | 3.59 | 1.76-7.32 | < .001 |
| Leukocyte count | 0.70 | 0.35-1.38 | .30 |
| Peripheral blasts | 1.53 | 0.89-2.61 | .12 |
| Constitutional symptoms | 1.58 | 0.91-2.73 | .10 |
*
Referent category is low risk for each covariate.