Table 1.
Yeast thiol-oxidoreductases
| Systematic Name |
Standard Name |
Redox Motif |
Redox Motif Position |
Secondary Structure |
Functions |
|---|---|---|---|---|---|
| YCL043C | PDI1 | CxxC, CxxC |
60, 405 | β-CGHC-α β-CGHC-α |
Protein disulfide isomerase |
| YCL035C | GRX1 | CxxC | 26 | β-CPYC-α | Glutaredoxin |
| YCR083W | TRX3 | CxxC | 54 | β-CGPC-α | Mitochondrial thioredoxin |
| YDR286C | YDR286C | CxxC | 30 | β-CGLC-α | Thioredoxin |
| YDR513W | GRX2 | CxxC | 60 | β-CPYC-α | Glutaredoxin |
| YGR029W | ERV1 | CxxC, CxxC |
29, 129 | -CRSCα, α-CNWC-α |
Mitochondrial biogenesis |
| YGR209C | TRX2 | CxxC | 30 | β-CGPC-α | Thioredoxin |
| YIL005W | EPS1 | CxxC, CxxC |
59, 199 | β-CPHC-α, β-CDKC-α |
Protein disulfide isomerase |
| YLR043C | TRX1 | CxxC | 29 | β-CGPC-α | Thioredoxin |
| YLR364W | GRX8 | CxxC | 24 | β-CPDC-α | Glutaredoxin |
| YML130C | ERO1 | CxxC, CxxC |
348, 351 | α-CVQC-α α-CDRC-α |
Involved in protein disulfide bond formation in the ER |
| YOL088C | MPD2 | CxxC | 55 | β-CQHC-α | Thiol-disulfide isomerase |
| YOR288C | MPD1 | CxxC | 58 | β-CGHC-α | Thiol-disulfide isomerase |
| YML019W | OST6 | CxxC | 77 | β-CQLC-α | Subunit of N-oligosaccharyltransferase complex |
| YOR085W | OST3 | CxxC | 72 | β-CSLC-α | Subunit of N-oligosaccharyltransferase complex |
| YDR353W | TRR1 | CxxC | 141 | -CAVC-α | Cytosolic thioredoxin reductase |
| YPR037C | ERV2 | CxxC | 120 | α-CGEC-α | Erv2 |
| YLR109W | AHP1 | SxxC | 58 | β-SPTC-α | Peroxiredoxin |
| YDR453C | TSA2 | SxxC | 44 | β- SFVC-α | Peroxiredoxin |
| YBR014C | GRX7 | CxxS | 108 | β-CPYS-α | Monothiol glutaredoxin |
| YDL010W | GRX6 | CxxS | 136 | β-CSYS-α | Monothiol glutaredoxin |
| YDR098C | GRX3 | CxxS | 211 | β-CGFS-α | Monothiol glutaredoxin |
| YER174C | GRX4 | CxxS | 171 | β-CGFS-α | Monothiol glutaredoxin |
| YPL059W | GRX5 | CxxS | 60 | β-CGFS-α | Monothiol glutaredoxin |
| YDR518W | EUG1 | CxxS, CxxS |
62, 405 | β-CLHS-α, β-CIHS-α |
Protein thiol-disulfide isomerase |
| YCL033C | MXR2 | CxxS | 157 | -CVNS- | Methionine-R sulfoxide reductase |
| YBR244W | GPX2 | CxxT | 36 | β-CGFT-α | Glutathione peroxidase |
| YGR154C | GTO1 | CxxT | 30 | β- CPFT-α | Glutathione S-transferase |
| YIR037W | HYR1 | CxxT | 35 | β- CGFT-α | Glutathione peroxidase |
| YKL026C | GPX1 | CxxT | 35 | β- CAFT-α | Glutathione peroxidase |
| YBL064C | PRX1 | TxxC | 87 | β- TPVC-α | Peroxiredoxin |
| YIL010W | DOT5 | TxxC | 103 | β- TPGC-α | Peroxiredoxin |
| YML028W | TSA1 | TxxC | 44 | β- TFVC-α | Peroxiredoxin |
| YER042W | MXR1 | CxxG | 24 | β- CFWG-α | Methionine-S sulfoxide reductase |