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Effect of enalapril and metformin treatment on hepatic total CYP epoxygenase (EET + DHET) metabolic activity (A), hepatic CYP ω-hydroxylase (20-HETE) metabolic activity (B), renal total CYP epoxygenase (EET + DHET) metabolic activity (C), and renal CYP ω-hydroxylase (20-HETE) metabolic activity (D) (standard diet: no treatment, n = 11; metformin: n = 6; enalapril: n = 6; high-fat diet: n = 6/group). *P < 0.05 vs. no treatment/standard diet; #P < 0.05 vs. no treatment/high-fat diet.
