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Expression of small ubiquitin-related modifier protein (SUMO) transcripts in mouse islets. Quantitative real-time RT-PCR shows increased expression of SUMO-1 transcripts in mouse islets exposed to high glucose. The fold change in expression of SUMO transcripts and Ubc-9 from islets in 16 mM glucose and 5 mM glucose is shown; n = 3 independent experiments, and error bars indicate means ± SD. Student's t-test: P = 0.01–0.05 (*) and 0.001–0.01 (**). β-Actin was used as an internal control.
