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No change in apoptosis in Yap+/− mice. A: caspase-3 activity measured in cytoplasmic extracts obtained from livers of Yap+/+ and Yap+/− at PND15 and PND30 (n = 5). B: representative photomicrographs of TUNEL assay performed on frozen section of Yap+/+ and Yap+/− livers at PND15. Arrowheads point to cells in apoptosis.
