Table 4.
CD1 Mice |
B6 Mice |
|||||
---|---|---|---|---|---|---|
E13.5 | E15.5 | E17.5 | E13.5 | E15.5 | E17.5 | |
No. of placentas/group | 8 | 9 | 8 | 7 | 10 | 8 |
Vascular volume, mm3 | 1.51 ± 0.09a | 2.08 ± 0.16b | 2.41 ± 0.19b | 1.73 ± 0.08a | 2.14 ± 0.07b | 2.74 ± 0.16c |
Vascular depth, mm | 0.92 ± 0.03a | 1.15 ± 0.02b | 1.30 ± 0.04b | 0.86 ± 0.04a | 1.01 ± 0.04a,* | 1.32 ± 0.04b |
Vascular span, mm | 6.27 ± 0.10 | 6.58 ± 0.11 | 6.48 ± 0.07 | 6.44 ± 0.07 | 6.25 ± 0.07 | 6.66 ± 0.05 |
Umbilical artery diameter, mm | 0.32 ± 0.02a,* | 0.46 ± 0.01b | 0.54 ± 0.01c | 0.39 ± 0.02a | 0.51 ± 0.02b | 0.50 ± 0.01b |
No. of vessel segments | 1136 ± 111 | 1117 ± 79 | 1164 ± 78 | 1358 ± 52 | 1368 ± 80 | 1359 ± 61 |
Total length of vasculature, mm | 261 ± 14a | 291 ± 15a | 324 ± 14b | 278 ± 6a | 299 ± 8a | 332 ± 9a |
Diameter scaling coefficient | −2.82 ± 0.10a | −2.77 ± 0.06a | −3.04 ± 0.25a | −3.03 ± 0.04a | −3.05 ± 0.08a | −3.51 ± 0.21b,* |
Length-to-diameter ratio | 2.67 ± 0.70 | 2.82 ± 0.63 | 2.91 ± 0.82 | 2.36 ± 0.59 | 2.32 ± 0.53 | 2.37 ± 0.65 |
Data are means ± SE.
Different letters show a significant difference between gestational ages (P < 0.05);
P < 0.05, significant differences between strains at the same gestational age as determined by two-way ANOVA followed by Tukey post hoc tests.