The effect of OVA on bronchoalveolar lavage fluid (BALF) cellularity (PN4 mice). HIF-1α-sufficient (white and diagonally hatched bars) and PN4 HIF-1α-deficient (black and horizontally hatched) mice were sensitized/challenged with saline (white and black bars) or OVA (diagonally and horizontally hatched bars). Total cells, as well as the numbers of macrophages (Macs), eosinophils (Eos), neutrophils (PMNs), and lymphocytes (Lymph) were determined from BALF. Values are means ± SE (n ≥ 9). a, Significantly different from HIF-1α-sufficient within treatment P < 0.05; b, significantly different from saline treated within genotype P < 0.05.