Table 1.
Contractility indices
| Young |
Mature |
Old |
Oldest-Old |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SE | Note | Percent | Mean | SE | Percent | Mean | SE | Percent | Mean | SE | Percent | |
| Pmax, cm/W (P = 0.1431) | 48 | 2.5 | 100% | 47 | 1.2 | 100% | 44 | 1.7 | 100% | 44 | 2.3 | 100% | |
| Pdet at Pmax, cm/W (P = 0.0149) | 10 | 2.5 | 2 | 21% | 20 | 2.5 | 43% | 17 | 2.2 | 39% | 21 | 3.8 | 47% |
| PTI, voiding contraction, cm·W−1·s−1 | |||||||||||||
| Total (P = 0.0020) | 376 | 64.8 | 2, 4 | 100% | 612 | 48.5 | 100% | 587 | 37.5 | 100% | 892 | 171.0 | 100% |
| Abdominal (P = 0.1231) | 1.8 | 0.52 | 0.5% | 2.4 | 0.70 | 0.4% | 0.4 | 0.27 | 0.1% | 2.0 | 2.00 | 0.2% | |
| Compliance (P = 0.00480) | 124 | 34.2 | 2, 3 | 33% | 149 | 14.6 | 24% | 189 | 19.8 | 32% | 333 | 105.4 | 37% |
| Detrusor (P = 0.0019) | 251 | 35.4 | 2, 4 | 67% | 462 | 44.9 | 75% | 399 | 26.2 | 68% | 558 | 79.5 | 63% |
| PTI, during flow, cm·W−1·s−1 | |||||||||||||
| Total (P = 0.0094) | 112 | 12.4 | 2, 3 | 100% | 193 | 26.5 | 100% | 193 | 13.2 | 100% | 183 | 30.0 | 100% |
| Abdominal (P = 0.1231) | 1.8 | 0.52 | 1.6% | 2.4 | 0.70 | 1.2% | 0.4 | 0.27 | 0.2% | 2.0 | 2.00 | 1.1% | |
| Compliance (P = 0.0600) | 43 | 5.8 | 38% | 47 | 9.4 | 24% | 67 | 10.2 | 35% | 81 | 25.2 | 44% | |
| Detrusor (P = 0.0333) | 67 | 14.2 | 2 | 60% | 145 | 25.9 | 75% | 126 | 11.1 | 65% | 100 | 32.2 | 55% |
| Detrusor voiding PTI work and power | |||||||||||||
| Work, cm·W−1· ml−1 (P = 0.0006) | 1.60 | 0.86 | 2, 3, 4 | 10.0 | 2.60 | 11.8 | 2.75 | 12.2 | 3.37 | ||||
| Power, cm·W−1· ml−1·s−1 (P = 0.0024) | 0.340 | 0.168 | 2, 3, 4 | 1.82 | 0.45 | 2.03 | 0.48 | 2.08 | 0.71 | ||||
Bladder and detrusor pressures, pressure-time integrals (PTI), and PTIdetrusor-derived work (W) and power. Calculations described in the text. Means ± SE are reported. Component contribution to total percentages reported for detrusor pressure at maximum voiding bladder pressure (Pdet at Pmax) and PTI during voiding contraction and during flow. Comparisons between groups by ANOVA with Bonferroni or Kruskal-Wallace with Dunn's post hoc tests, as appropriate. Only Young vs. other groups demonstrated significant differences, as indicated in notes column: 2vs. Mature; 3vs. Old; 4vs. Oldest-Old.