Table 1.
Demographics and clinical characteristics of IPAH study subjects
| Subjects with IPAH | |
|---|---|
| n | 154 |
| Mean age, yr | 50.8 ± 13.5 |
| Sex (female) | 114 |
| FEV1, 1 | 2.1 ± 0.1 |
| FEV1, %predicted | 70 ± 1.5 |
| FVC, 1 | 2.8 ± 0.1 |
| FEV, %predicted | 76 ± 1.7 |
| MPAP, mmHg | 51.2 ± 2 |
| PVR, Wood units | 10 ± 0.6 |
| CI, l·min−1·m−2 | 2.4 ± 0.1 |
| AST, mg/dl | 28.3 ± 1.5 |
| ALT, mg/dl | 22.5 ± 1.5 |
| Bilirubin, mg/dl | 0.9 ± 0.1 |
| Creatinine, mg/dl | 1.1 ± 0.1 |
| Medications | No. of patients |
| Prostacyclin | 54 |
| Other medications | 47 |
Values are means ± SE. IPAH, idiopathic pulmonary arterial hypertension; FEV1, forced expiratory volume in 1 s; MPAP, mean pulmonary arterial pressure; PVR, pulmonary vascular resistance; CI, cardiac index; AST, aspartate aminotransferase; ALT, alanine aminotransferase.