Table 1. The profiles of the patients included for analysis of renal biopsies.

	MGA (n = 9)	MCD (n = 8)	LN (n = 17)	IgAN (n = 19)
Mean age (years)	42.2±7.6	41.5±9.8	35.1±3.7	38.6±4.9
Gender (male/female)	4/5	3/5	2/15	8/11d
BMI (kg/m2)	23.3±1.0	24.6±2.1	22.5±0.9	22.1±0.8
Laboratory data
eGFR (ml/min/1.73 m2)	83.0±9.1	91.0±12.9	87.9±7.7	80.9±7.2
Urinary protein (g/day)	0.7±0.5	7.0±2.0a	2.3±0.7b , c	0.9±0.7c , e
Hematuria (/hpf)	0.6±0.2	1.4±0.3	40.9±9.7a	39.9±9.2a , d
Serum IgA (mg/dl)	235.0±32.5	245.5±36.9	259.5±24.9	295.9±23.6
Plasma glucose (mg/dl)	97.6±4.8	125.4±22.2	101.2±7.1	101.6±6.8
HbA1c (%)	5.6±0.3	5.5±0.3	5.4±0.2	5.1±0.2
Total cholesterol (mg/dl)	208.1±24.8	355.8±48.7b	221.1±20.7c	183.6±19.5c , f
HDL cholesterol (mg/dl)	74.2±13.0	75.8±7.3	51.2±6.3c	61.1±5.7
LDL cholesterol (mg/dl)	112.4±13.1	237.5±43.1b	128.4±18.3d	97.3±15.7d , f
LDL/HDL ratio	1.6±0.2	3.2±0.7b	2.5±0.3	1.8±0.3d
Triglycerides (mg/dl)	126.2±22.0	202.0±28.1	182.3±20.2b	135.0±18.6
Pathological data
IgA deposition (grade)	0.1±0.1	0.3±0.1	1.4±0.7a , c	2.3±0.1a , c , e
Global sclerosis (%)	1.0±1.3	0.1±0.1	2.2±0.7	2.4±0.7
Mesangial proliferation (%)	0.0±0.0	0.0±0.0	6.9±0.8a , c	1.5±0.8b , d , e
Mesangial sclerosis (%)	0.0±0.0	0.0±0.0	0.8±0.2	1.0±0.2a , c
Crescent formation (%)	0.0±0.0	0.0±0.0	2.1±0.5	1.3±0.5b , d , f
Adhesion (%)	0.0±0.0	0.0±0.0	1.8±0.6	3.6±0.6a , c
Cell infiltration (grade)	0.2±0.2	0.1±0.1	0.9±0.2b , c	0.6±0.2d
Tubular atrophy (grade)	0.6±0.2	0.5±0.3	1.1±0.2	1.5±0.2b , d
Interstitial fibrosis (grade)	0.6±0.2	0.3±0.2	1.1±0.2d	1.6±0.2b , c
Vascular sclerosis (grade)	0.7±0.2	0.8±0.4	0.8±0.2	0.9±0.2

MGA, minor glomerular abnormalities; MCD, minimal change disease; LN, lupus nephritis; IgAN, IgA nephropathy; eGFR, estimated glomerular filtration rate; BMI, body mass index; HbA1c, hemoglobin A1c; HDL, high density lipoprotein; LDL, low density lipoprotein.

^a: P<0.01,

^b: P<0.05 vs. MGA.

^c: P<0.01,

^d: P<0.05 vs. MCNS.

^e: P<0.01,

^f: P<0.05 vs. LN.