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Optimal cut-off values for cytokines, with sensitivity, specificity and positive and negative predictive values
| Cut-off value | Sensitivity | Specificity | PPV | NPV | |
|---|---|---|---|---|---|
| Interleukin-6 | 27.2 pg/ml | 70.5 | 60.4 | 0.057 | 0.984 |
| Interleukin-10 | 3.15 pg/ml | 67.3 | 58.1 | 0.051 | 0.981 |
| LBP | 22.45 μg/ml | 55.2 | 66.6 | 0.053 | 0.978 |
Positive predictive values (PPV) and negative predictive values (NPV) were obtained using Bayes' formula, with a prevalence of 0.0326. LBP, lipopolysaccharide-binding protein.
