Table 5. Transcription factor genes downregulated in BMDH.
Underexpressed | ||
TF-Expt ID1 | Genes2 | p-val3 |
EP300-20729851 | 28 | 1.4E-04 |
EP300-21415370 | 13 | 0.01 |
HNF4A-19761587 | 26 | 1.7E-08 |
HNF4A-19822575 | 97 | 6.7E-20 |
KLF4-18358816 | 27 | 1.1E-05 |
KLF4-18555785 | 52 | 8.0E-15 |
KLF4-19030024 | 18 | 0.007 |
MYC-18358816 | 59 | 5.9E-13 |
MYC-18555785 | 29 | 8.7E-10 |
MYC-18940864 | 9 | 0.05 |
MYC-19030024 | 81 | 3.0E-23 |
MYC-19079543 | 28 | 2.0E-07 |
MYC-19915707 | 29 | 0.01 |
MYC-20876797 | 16 | 0.02 |
NANOG-16518401 | 34 | 0.008 |
NANOG-18347094 | 20 | 0.02 |
NANOG-18358816 | 17 | 0.002 |
NANOG-18555785 | 10 | 0.003 |
NANOG-18692474 | 50 | 3.4E-10 |
NANOG-21062744 | 12 | 0.007 |
POU5F1-18347094 | 35 | 1.7E-07 |
POU5F1-18358816 | 11 | 0.009 |
POU5F1-18555785 | 16 | 6.9E-07 |
POU5F1-18692474 | 66 | 1.7E-12 |
POU5F1-18700969 | 9 | 0.01 |
RCOR1-19997604 | 25 | 0.008 |
REST-18959480 | 29 | 0.008 |
REST-19997604 | 27 | 4.0E-04 |
SFPI1-20887958 | 44 | 1.1E-10 |
SMAD1-18555785 | 10 | 0.006 |
SMAD2-18955504 | 26 | 2.4E-04 |
SMAD3-18955504 | 26 | 2.4E-04 |
SMAD4-19686287 | 6 | 0.04 |
SOX2-18358816 | 10 | 0.03 |
SOX2-18555785 | 8 | 0.01 |
SOX2-18692474 | 55 | 2.2E-11 |
SOX2-19030024 | 17 | 4.1E-05 |
SOX2-20726797 | 30 | 7.7E-04 |
SOX2-21211035 | 43 | 8.8E-06 |
ChEA software was used to identify transcription factors that could regulate the expression of BMDH genes with respect to microdissected cells (hematopoietic and hepatocytes) and mouse macrophages, B cells and liver tissue.
TF: transcription factor symbol; Expt ID: PubMed ID for the publication.
Number of the BMDH genes regulated by the TF.
Significance of the gene overlapping.