Figure 1. Genomic region of human chromosome 17p13.3 harbouring the SERPINF1 gene and HapMap linkage disequilibrium data of common (minor allele frequency ≥0.05) informative SNPs within this region.

The SERPINF1 gene consists of 8 exons and 7 introns and spans 15.6 kb from nucleotide position 1,612,009 to nucleotide position 1,627,617. The analyzed region additionally included 4 kb of the 5′-flanking region and 1.5 kb of the 3′-flanking region. This genomic region did not overlap with other known gene loci. The locations of the five tagging SNPs (highlighted by boxes) are indicated. Linkage disequilibrium data, i.e., r²-values only, are presented as numbers in the diamonds (100 = 1.00) and different diamond shadings (white – low linkage; black – high linkage; grey – in between).