Table 2.
Correlation between hCG, LH-receptor and FSH-receptor expression in all ovarian cancer subtypes
| Correlations | ||||||||
|---|---|---|---|---|---|---|---|---|
| hCG (Int) | hCG (IRS) | LH-R (Int) | LH-R (IRS) | FSH-R (Int) | FSH-R (IRS) | |||
| Spearman's rho | hCG (Int) | Correlation Coefficient | 1.00 | 0.94** | 0.13 | 0.19* | -0.09 | 0.01 |
| Sig. (2-tailed) | < 0.01 | 0.04 | ||||||
| hCG (IRS) | Correlation Coefficient | 0.94** | 1.00 | 0.12 | 0.19* | -0.01 | 0.09 | |
| Sig. (2-tailed) | < 0.01 | 0.04 | ||||||
| N (Int/IRS) | 143 | 143 | 116 | 116 | 114 | 113 | ||
| LH-R (Int) | Correlation Coefficient | 0.13 | 0.12 | 1.00 | 0.90** | 0.23* | 0.23* | |
| Sig. (2-tailed) | < 0.01 | 0.01 | 0.01 | |||||
| LH-R (IRS) | Correlation Coefficient | 0.19* | 0.19* | 0.90** | 1.00 | 0.21* | 0.24* | |
| Sig. (2-tailed) | 0.04 | 0.04 | < 0.01 | 0.03 | 0.01 | |||
| N (Int/IRS) | 116 | 116 | 120 | 120 | 116 | 115 | ||
| FSH-R (Int) | Correlation Coefficient | -0.09 | -0.01 | 0.23* | 0.21* | 1.00 | 0.87** | |
| Sig. (2-tailed) | 0.01 | 0.03 | 0.01 | |||||
| FSH-R (IRS) | Correlation Coefficient | 0.002 | 0.09 | 0.23* | 0.24* | 0.87** | 1.00 | |
| Sig. (2-tailed) | 0.01 | 0.01 | < 0.01 | |||||
| N (Int/IRS) | 113 | 113 | 115 | 115 | 117 | 117 | ||
We found a significant correlation between hCG and LH-receptor expression whereas hCG expression and FSH-receptor expression do not correlate with each other. (IRS = immunoreactive score, Int = staining intensity)
** Correlation is significant at the 0.01 level (2-tailed)
* Correlation is significant at the 0.05 level (2-tailed)