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. 2012 Mar 23;7(3):e34223. doi: 10.1371/journal.pone.0034223

Figure 6. Consequences of ERR inhibition on TAL functions.

Figure 6

After seven days of treatment with DES (100 µg/mouse)/day or vehicle, the mRNA level of NCC (A), renin (B) and NKCC2 (C) were assessed on whole kidney RNA extracts. NKCC2 protein level were evaluated by Western Blot (D and E) from kidney homogenates of control or DES-treated mice. (F) Following the same protocol of DES treatment, furosemide was injected in all mice at day 7 (DES or control groups) and urine was collected on a period of 90 minutes. Results are shown as the mean±s.e.m (n = 9). Non-paired Student t-test, * p<0.05.