Table 4. Genome-wide significant SNPs for ETEC F4ab and F4ac susceptibility.
SNP name | Chr. | Position (bp)a | Nearest geneb | p valuec | ||
Name | Distance (bp) | F4ab | F4ac | |||
M1GA0027009 | 0 | NA | NA | NA | 1.32E-06 | 2.77E-05 |
DIAS0003141 | 0 | NA | NA | NA | 6.47E-06 | NS |
ALGA0122702 | 0 | NA | NA | NA | 7.01E-07 | NS |
ALGA0106843 | 0 | NA | NA | NA | 9.08E-07 | NS |
DIAS0001226 | 0 | NA | NA | NA | 1.05E-06 | NS |
MARC0066682 | 0 | NA | NA | NA | 1.95E-06 | 2.61E-05 |
M1GA0027131 | 0 | NA | NA | NA | 1.99E-06 | 4.55E-05 |
DIAS0004305 | 0 | NA | NA | NA | 9.22E-08 | NS |
MARC0101456 | 0 | NA | NA | NA | 2.22E-06 | NS |
ALGA0109098 | 0 | NA | NA | NA | 4.71E-06 | NS |
MARC0095534 | 13 | 100411276 | SENP5 | 35104 | 6.47E-06 | 9.18E-06 |
H3GA0037333 | 13 | 100853976 | TNK2 | 31111 | 3.25E-05 | NS |
MARC0012378 | 13 | 100878960 | TNK2 | 6127 | 7.01E-07 | 8.97E-07 |
M1GA0017682 | 13 | 100885039 | TNK2 | 48 | 9.08E-07 | 8.14E-07 |
ASGA0058885 | 13 | 100916770 | TNK2 | within | 1.05E-06 | 1.11E-06 |
MARC0067282 | 13 | 101488856 | ZNF148 | within | 1.95E-06 | 2.73E-05 |
MARC0099692 | 13 | 101550380 | ZNF148 | 8634 | 1.99E-06 | 2.72E-05 |
ALGA0072075 | 13 | 101582070 | HEG1 | 31668 | 7.22E-08 | 1.94E-07 |
MARC0002946 | 13 | 101604226 | HEG1 | 9512 | 2.22E-06 | 9.87E-06 |
ASGA0058925 | 13 | 101659492 | HEG1 | within | 4.71E-06 | 3.03E-06 |
ASGA0089965 | 13 | 101783439 | HEG1 | 18479 | 1.77E-05 | 5.93E-06 |
ASGA0091537 | 13 | 101818006 | MUC13 | 16416 | 2.32E-05 | 5.72E-06 |
ALGA0106330 | 13 | 101846502 | MUC13 | within | 3.23E-05 | 8.97E-06 |
H3GA0037348 | 13 | 101925778 | ITGB5 | within | 4.81E-05 | 1.64E-05 |
H3GA0037351 | 13 | 101955862 | ITGB5 | within | 2.59E-05 | 9.06E-06 |
MARC0096736 | 13 | 102039909 | UMPS | within | 2.16E-05 | NS |
DIAS0001297 | 13 | 102070045 | UMPS | 21938 | 3.67E-05 | NS |
H3GA0037388 | 13 | 103041803 | MYLK | 144363 | 1.03E-05 | 2.68E-05 |
Derived from the most recent porcine genome sequence assembly (Sscrofa9.2). NA: not available.
The nearest known gene to the significant SNP;
Obtained from the empirical distribution of test statistics via data permutation with 10,000 replicates. The thresholds for 5% (1%) genome-wise significance are 5.72E-05 (1.57E-06) for susceptibility to ETEC F4ab and 5.76E-05 (2.28E-06) for susceptibility to ETEC F4ac. NS: not significant.