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. 2012 Mar 23;7(3):e32127. doi: 10.1371/journal.pone.0032127

Table 4. Genome-wide significant SNPs for ETEC F4ab and F4ac susceptibility.

SNP name Chr. Position (bp)a Nearest geneb p valuec
Name Distance (bp) F4ab F4ac
M1GA0027009 0 NA NA NA 1.32E-06 2.77E-05
DIAS0003141 0 NA NA NA 6.47E-06 NS
ALGA0122702 0 NA NA NA 7.01E-07 NS
ALGA0106843 0 NA NA NA 9.08E-07 NS
DIAS0001226 0 NA NA NA 1.05E-06 NS
MARC0066682 0 NA NA NA 1.95E-06 2.61E-05
M1GA0027131 0 NA NA NA 1.99E-06 4.55E-05
DIAS0004305 0 NA NA NA 9.22E-08 NS
MARC0101456 0 NA NA NA 2.22E-06 NS
ALGA0109098 0 NA NA NA 4.71E-06 NS
MARC0095534 13 100411276 SENP5 35104 6.47E-06 9.18E-06
H3GA0037333 13 100853976 TNK2 31111 3.25E-05 NS
MARC0012378 13 100878960 TNK2 6127 7.01E-07 8.97E-07
M1GA0017682 13 100885039 TNK2 48 9.08E-07 8.14E-07
ASGA0058885 13 100916770 TNK2 within 1.05E-06 1.11E-06
MARC0067282 13 101488856 ZNF148 within 1.95E-06 2.73E-05
MARC0099692 13 101550380 ZNF148 8634 1.99E-06 2.72E-05
ALGA0072075 13 101582070 HEG1 31668 7.22E-08 1.94E-07
MARC0002946 13 101604226 HEG1 9512 2.22E-06 9.87E-06
ASGA0058925 13 101659492 HEG1 within 4.71E-06 3.03E-06
ASGA0089965 13 101783439 HEG1 18479 1.77E-05 5.93E-06
ASGA0091537 13 101818006 MUC13 16416 2.32E-05 5.72E-06
ALGA0106330 13 101846502 MUC13 within 3.23E-05 8.97E-06
H3GA0037348 13 101925778 ITGB5 within 4.81E-05 1.64E-05
H3GA0037351 13 101955862 ITGB5 within 2.59E-05 9.06E-06
MARC0096736 13 102039909 UMPS within 2.16E-05 NS
DIAS0001297 13 102070045 UMPS 21938 3.67E-05 NS
H3GA0037388 13 103041803 MYLK 144363 1.03E-05 2.68E-05
a

Derived from the most recent porcine genome sequence assembly (Sscrofa9.2). NA: not available.

b

The nearest known gene to the significant SNP;

c

Obtained from the empirical distribution of test statistics via data permutation with 10,000 replicates. The thresholds for 5% (1%) genome-wise significance are 5.72E-05 (1.57E-06) for susceptibility to ETEC F4ab and 5.76E-05 (2.28E-06) for susceptibility to ETEC F4ac. NS: not significant.