Table 3. Association of ADAM23 intronic SNP (BICF2P890779 at 18,123,961 bp) with epilepsy in 9 different breeds.
Breed | N cases+N controls | F_A1 (allele A) | F_U2 (allele A) | P | OR |
Belgian Shepherd | 116+130 | 0.76 | 0.49 | 9.70E-10 | 3.3 |
Kromfohrländer | 23+18 | 0.93 | 0.67 | 3.44E-03 | 6.5 |
Whippet | 24+26 | 0.81 | 0.60 | 0.018 | 2.9 |
Finnish Spitz | 62+81 | 1.00 | 0.98 | 0.13 | NA |
Lagotto Romagnolo | 23+23 | 0.35 | 0.48 | 0.20 | 0.6 |
Miniature Pinscher | 22+20 | 0.89 | 0.80 | 0.27 | 2.0 |
Border Terrier | 42+40 | 0.93 | 0.89 | 0.36 | 1.6 |
Schipperke | 63+48 | 0.99 | 1.00 | 0.38 | NA |
Finnish Lapphund | 44+60 | 0.79 | 0.82 | 0.58 | 0.8 |
Frequency of the minor allele (based on GWAS controls) in affected individuals.
Frequency of the minor allele (based on GWAS controls) in unaffected individuals.
Frequencies of allele A are shown for each breed. P-values<0.05 are bolded.