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Mean change in forearm blood flow (FBF) from baseline values immediately preceding ACh infusion before and after concomitant infusion with l-NMMA, in women and men in the low-sodium (left panel) and high-sodium (right panel) cohorts. l-NMMA caused a significant decrease in the FBF response to ACh in both sexes and diets. *The NO component of ACh-induced vasodilation was significant for a sex-by-sodium interaction (P = 0.034). Error bars denote standard error of the mean (SE).
