Table 2.

Results of the final HR50 training response regression model and conditional heritability analysis

					Regression Model
SNP	Chromosomes	Map	Frequency of Common Allele	Nearest Gene Locus*	Partial R2	R2 model	P value	Remaining Heritability, %
rs2979481	8	30,382,328	0.645	RBPMS	0.0605	0.0605	8.1 × 10−8	24.6
rs6432018	2	9,639,347	0.524	YWHAQ	0.0457	0.1062	5.0 × 10−7	20.0
rs2253206	2	208,100,223	0.522	CREB1	0.0447	0.1509	2.2 × 10−6	14.8
rs1560488	4	90,444,858	0.791	GPRIN3	0.0423	0.1932	2.4 × 10−6	8.6
rs10248479	7	115,395,591	0.876	TFEC	0.0333	0.2264	1.1 × 10−5	6.8
rs857838	1	157,017,174	0.60	OR6N2	0.0302	0.2566	1.8 × 10−5	5.0
rs909562	6	16,238,312	0.875	MYLIP	0.0296	0.2861	1.7 × 10−5	0.7
rs4759659	12	129,403,241	0.538	PIWIL1	0.0276	0.3138	2.3 × 10−5	1.6
rs2057368	14	54,373,759	0.804	GCH1	0.0238	0.3375	6.3 × 10−5	0
rs4498613	9	95,545,460	0.808	PHF2 (60 kb)	0.0218	0.3593	0.0001	NA

Remaining heritability, estimate when a given SNP (plus preceding SNPs) is included as covariate(s) in the MERLIN heritability model; N/A, not applicable.

^*Values in parentheses indicate distance between the SNP and the nearest gene locus; if no distance is given, the SNP is located within the gene.