Table 1.
Regions of decreased grey matter volume in CADASIL compared with control
| Cluster | MNI-space | K value | p value | Z value | Side | Lobe | Anatomic region | ||
|---|---|---|---|---|---|---|---|---|---|
| x | y | z | |||||||
| 1 | −51 | 3 | −36 | 1,193 | 0.000* | 3.95 | L | Temporal | Middle temporal gyrus |
| 2 | 51 | 6 | −39 | 427 | 0.02* | 3.66 | R | Temporal | Middle temporal gyrus |
| 3 | −57 | 22 | 6 | 150 | 0.27 | 4.3 | L | Frontal | Inferior frontal gyrus |
| 4 | 18 | −27 | 2 | 50 | 1 | 4.15 | R | Thalamus (Pulvinar) | |
| 5 | 65 | −26 | 2 | 30 | 1 | 4.05 | R | Temporal | Superior temporal gyrus |
| 7 | 30 | 9 | −11 | 356 | 0.000* | 5.21 | R | Caudate nucleus | |
MNI Montreal Neurological Institute, x, y, z coordinates of the primary maximum of the cluster, K value number of voxels in the cluster, L left hemisphere, R right hemisphere
* Clusters surviving a statistical threshold of p < 0.05, FDR corrected