Table 1.
In vitro clonogenic MM growth of CD138−/CD34− cells isolated from primary patient samples
| No. | Colony formation, no. (%) | No. of colonies/105 cells, mean (range) | |
|---|---|---|---|
|
MM
| |||
| BM | 24 | 21 (88) | 24 (4–43) |
|
| |||
| PB | 4 | 2 (50) | 7.5 (3–12) |
|
PCL
| |||
| BM | 2 | 2 (100) | 42 (17–66) |
|
| |||
| PB | 2 | 2 (100) | 30 (12–49) |
|
MGUS
| |||
| BM | 6 | 3 (50) | 5 (3–8) |
|
| |||
| Total | 32 | 26 (81) | ND |
P < .01 for comparison of no. of colonies/105 cells from bone marrow samples in MM, PCL, and MGUS groups by ANOVA.
BM indicates bone marrow; PB, peripheral blood; PCL, plasma cell leukemia or advanced MM; MGUS, monoclonal gammopathy of unknown significance; and ND, not determined.