Table 1.
Statistical values for each experiment
| Variable | Auditory threshold (ABR) | Experiment 1: N40 baseline | Experiment 2: N40 haloperidol | Experiment 3: N40 amphetamine |
|---|---|---|---|---|
| Genotype (1) | F(1, 22)<0.02, P=0.898 | F(1, 22)=23, P<0.001 | F(1, 22)=0.02, P=0.892 | F(1, 22)=6.1, P=0.022 |
| Intensity (2) | F(5, 110)=89, P<0.001 | F(2, 44)=22, P<0.001 | F(2, 44)=27, P<0.001 | F(2, 44)=45, P<0.001 |
| Drug exposure (3) | — | — | F(2, 44)=11, P<0.001 | F(3, 66)=11, P<0.001 |
| 1×2 | F(5, 110)=2.8, P=0.021 | F(2, 44)=11, P<0.001 | F(2, 44)=3.0, P=0.061 | F(2, 44)=6.1, P=0.004 |
| 1×3 | — | — | F(2, 44)=6.5, P=0.003 | F(3, 66)=3.8, P=0.015 |
| 2×3 | — | — | F(4, 88)=1.4, P=0.241 | F(6, 132)=4.4, P<0.001 |
| 1×2×3 | — | — | F(4, 88)=0.7, P=0.617 | F(6, 132)=3.9, P=0.001 |
Variable 1 indicates genotype, variable 2 indicates intensity and variable 3 indicates drug condition (haloperidol or amphetamine) for experiments 2 and 3. Note, there are only two variables (genotype and intensity) in the baseline and threshold experiments. Significant main effects and interactions are highlighted in bold.