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Immunohistochemical stains for immunoglobulins confirm the nature of the crystalline inclusions within the histiocytes. a Immunostain for IgM heavy chain is strong and diffuse. b IgG heavy chain is diffuse but relatively weak. c Immunoreactivity for lambda light chain is strong within the histiocytes as well as in the plasma cells, which demonstrate IgM lambda light chain restriction. d Kappa light chain is weakly positive (×400 magnification)
