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The folding schemes of the UO22+-specific DNAzyme 39E and the Pb2+-specific DNAzyme 8–17 in response to different metal ions. a) The 39E–substrate sequence used in these FRET experiments; b) the folding scheme of the UO22+-specific DNAzyme 39E–substrate; c) the sequence of the 8–17–substrate sequence used in these FRET experiments; d) the folding scheme of the Pb2+-specific DNAzyme 8–17–substrate. The enzyme strand is shown in green and the substrate strand is shown in black.
