Table 1.
Parameter | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 (secondary PCL) |
---|---|---|---|---|---|
Age | 57 | 49 | 66 | 59 | 77 |
Sex | Female | Male | Male | Female | Male |
Extramedullary involvement | + | + | – | + | + |
Hemoglobin <8.5 g/dL | + | + | + | + | + |
Platelet <100 × 103/cumm | + | + | + | – | + |
Peripheral blood plasma cell count | 94% | 46% | 33% | 30% | 92% |
Bone marrow plasma cells >30% | + | + | + | + | + |
S. LDH >460 IU/dL | + | + | ND | + | + |
Albumin <3.5 g/dL | + | + | – | + | + |
Creatinine >2 mg/dL | – | + | + | + | – |
Type of monoclonal component | ND | IgG | ND | IgG | Non-secretory |
Immunophenotype | Positive markers = CD38 and kappa light chain. Negative markers = CD5, CD19, CD20, CD23,CD10, CD25, CD103, FMC-7 and lambda light chain. | ND | ND | ND | Positive markers-CD38 and kappa light chain. Negative markers CD20 and lambda light chain. |
S.LDH serum lactate dehydrogenasem, ND not done, IgG immunoglobulin G