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Pathogen-specific CD4+ T cell responses increase during the acute phase of infection. Data represent the mean frequency of cytokine-positive CD4+ T cells ± SEM; only upper error bars have been shown for clarity. Early reactivators are animals reactivating <17 wk post-SIV infection, and late reactivators are animals reactivating >26 wk post-SIV infection. Pre-SIV infection data from monkey 10405 were not available. hdMtb, high-dose M. tuberculosis.
